The Stout Lab is looking for a highly motivated postdoctoral research fellow to join the multidisciplinary laboratory within the Aging & Metabolism (A&M) Research Program at OMRF. The fellow will investigate the basic mechanisms that underlie gonadal aging and/or hypothalamic–pituitary–gonadal axis dysfunction with advancing age. The successful candidate will employ a wide range of techniques including the generation of novel mouse models, isotopic labeling, single-cell transcriptomics, spatial transcriptomics, histology & pathological assessments, and a variety of other cellular & molecular biology techniques. The candidate will present their data regularly in laboratory meetings, local seminars and symposiums, and will have opportunities to present their work at national conferences. A requirement of the position is that the candidate must demonstrate ethical behavior at all times, a high-level of scientific rigor, and must be detail-oriented and able to work independently and as part of a team.  

The Development Department is seeking a motivated, positive, self-starter intern to assist with all facets of Development including, but not limited to:   - Note writing, phone calls, new donor research - Assist with outside tours of labs and facilities - Assist with the OMRF Teen Leaders Program - Assist with annual donor events including 241 and the MS Advocate Award Dinner - Other general office administration (filing, scanning, copying, etc.)   This position reports directly to the Senior Director of Major Gifts and Outreach.

A postdoctoral research position is available in Dr. Jasim Ahamed’s laboratory to study the role of TGF-beta in organ fibrosis and cardiovascular disease (Antioxid Redox Signal. 2021 (PMID: 34619980); AIDS. 2020 Jun 1;34(7):989-1000 (PMID¨32167970); Blood Adv. 2019 Mar 12;3(5):777-788. (PMID: 30846427); Meyer et al. Blood 2012, 119:1064. (PMID:22134166). We are seeking individuals with experience in biochemistry, molecular biology, in vivo mouse models for cardiovascular disease, and ultrasound imaging techniques.    

1. Performs cleaning, sanitization, and preparation of caging and accessories by processing dirty and clean cages and equipment for a variety of laboratory animal species in a timely manner. 2. Operates equipment including autoclaves, mechanical washers, bedding dispenser, per department SOP's. 3. Perform daily maintenance requirements of equipment as per SOP's and notify supervisor of any equipment malfunctions. 4. Sanitize all areas of facility per department SOP's. 5. Maintain quality control records. 6. Observe SOP's for traffic flow within facility to prevent cross-contamination. 7. Assist with monitoring facility environment, notify supervisor of any problems detected. 8. Receive and store incoming supplies; maintain storage room. 9. Performs all other duties as assigned.   General Responsibilities 1. Performs, as directed, safety compliance and uses Personal Protective Equipment (PPE), as needed. 2. Participates in Quality Assessment (QA) and Quality Improvement (QI) programs, as directed. 3. Maintains positive working relationships as a team player through problem solving issues, speaking positively about others, listening attentively and observing the confidentiality of research needs. 4. Increases customer service knowledge, skill and ability by participating in departmental training program. 5. Delivers service that exceeds expectations by problem solving with other employees as appropriate 6. Maintains a clean and safe working environment.

The Ocañas Lab is hiring a Research Technician to contribute to projects focused on brain aging and neurodegeneration using in vivo mouse models. Primary responsibilities will include mouse colony management (breeding, genotyping, record keeping), molecular biology techniques (qPCR, sequencing library preparation), and regular lab maintenance tasks. Other skills will be added as needed to support the research program. In-depth training will be provided for all tasks (no advanced experience required).

The Major Gifts Officer (MGO) is a member of the Philanthropy and Community Relations team and is responsible for securing financial resources for OMRF. The primary focus is meeting and working with donors and prospects with significant giving capacity to accomplish their giving objectives in the form of major gifts. The MGO will engage in and be responsible for all aspects of the donor development cycle including donor identification, cultivation, solicitation, acknowledgment, and stewardship. This position reports directly to the Senior Director of Major Gifts and Outreach, under the strategic vision of the Vice President for Philanthropy and Community Relations.    Performance Measurements: - Identify major gift prospects. Analyze and predict a donor’s propensity, capacity and enthusiasm to give. - Gather pertinent data to determine the best candidates for the major gifts program. - Cultivate major gift prospects, investing the necessary time and energy to build relationships designed to understand the donor/prospect goals with the expressed purpose of alignment with OMRF’s mission and objectives. - Solicit major gift prospects. Moving prospective major donors along the donor pipeline ready to receive an appropriate ask based upon donor intent and interest. - Stewardship of major gift donors. Develop stewardship strategies that continue the major gift relationship for future gifts and planned giving opportunities. - Manage a portfolio of approximately 150-200 qualified relationships and apply a custom cultivation strategy for each donor. - Collaborate with team members on the creation of content for written communications including proposals, collateral, and stewardship reports. - Prioritize and complete ongoing tasks following established departmental guidelines and policies. - Track prospects and donor contacts in portfolio using organization tools and tracking methods via SalesForce.   Experience: - A proven fundraising track record, as well as possible history in finance, sales, and marketing - The ability to lead, work in a team setting, and work independently - Detailed and in-depth knowledge of fundraising, it’s impact and tax-laws associated - Comfort in researching and analyzing large groups of data to uncover prospects - Excellent verbal and written communication aptitude - Capable of handling numerous tasks at once and still meeting deadlines - Demonstrated history of securing major gifts over three or more years  

The Oklahoma Medical Research Foundation (OMRF) Multiple Sclerosis Center of Excellence is undergoing an exciting time of clinical and clinical research expansion through generous philanthropic support. We are recruiting two physician investigators with clinical research interests in investigator-initiated clinical trials, outcomes research, or other patient-oriented investigation to join our strong multi-disciplinary MS clinical care and research team. Building on strong clinical research infrastructure with longitudinal cohorts, a cadre of talented clinical coordinators/clinical research nurses, diverse aspects of clinical research informatics and a CAP-certified biorepository, we invite qualified candidates to apply for a clinical investigative position focusing on multiple sclerosis and related disorders. We are currently recruiting at the Assistant/Associate/Full Member level (Assistant/Associate/Full Professor equivalent). Talented candidates at all levels are encouraged to apply and will be considered.   Successful applicants will:   - Spearhead investigator-initiated, sponsor-led and/or NIH clinical trials - Provide comprehensive, optimal, science-driven multiple sclerosis patient care - Receive generous, multi-year start-up package with significant, sustained salary and research support - Collaborate with basic scientists interested in MS patient-oriented translational research - Interact closely with Oklahoma University Health Sciences Center faculty and participate in OUHSC house staff and medical training programs - Contribute toward and enjoy access to: - vibrant patient cohorts with associated patient care and clinical trials infrastructure - extensive autoimmune disease and control bio-specimen collections - outstanding OMRF and ACI Clinical and Research Core facilities   Arthritis and Clinical Immunology investigators have access to a number of outstanding OMRF core facilities, including and state-of-the-art clinical facilities. Extensive autoimmune disease and control sample collections are also available. Pilot programs are also available through the Oklahoma Shared Clinical & Translational Resources funding streams, as well as through the Oklahoma Center for Advancement of Science and Technology. Our clinicians provide outpatient care with no in-patient admission or consulting requirements.   OMRF (http://omrf.org) is an independent, not-for-profit biomedical research institute adjacent to the University of Oklahoma Health Sciences Center (OUHSC) campus in Oklahoma City. OMRF investigators enjoy close scientific interactions with OUHSC faculty and participate in OUHSC graduate programs. For more information about the OMRF MS Center of excellence, please visit: https://omrf.org/patient-studies/multiple-sclerosis/. For more information about the Arthritis and Clinical Immunology Research program, please visit: https://omrf.org/programs/arthritis-clinical-immunology-research-program/.  

The Montgomery Lab is a translational laboratory focused on understanding the mechanisms of complex diseases known to have genetic underpinnings and immune dysregulation. We have a particular interest in sarcoidosis, a granulomatous disorder that disproportionately affects women and people of African ancestry. We focus to better understand the pathogenesis of disease through immunological characterization and genomic profiling. We have large, complex datasets partnered with detailed clinical data to improve the lives of patients with of immune-mediated diseases. The successful candidate will be part of a dynamic team with synergistic skills and experiences and will be given the opportunity to develop projects that complement the overall directions of the group. The team utilizes high throughput assays, deep phenotyping, single cell genomic, proteomic, and computational and bioinformatics analyses. We also have access to high performance computational resources both in-house and through cloud-based resources. Trainees have the opportunity to participate in large, NIH-funded consortia like TOPMed. This position also allows for cross-training in the data sciences via the OMRF Center for Biomedical Data Sciences for which Dr. Montgomery is the Director. This is a mentored position for postdoctoral training. Individuals at this level plan, design and conduct research experiments; manage research projects; prepare reports and papers for publication, presentation and future research; contribute to grant writing and are encouraged to write applications for fellowships; learn the complexities of research lab management and participate in various lab activities. Benchmark Expectations - Conduct scientific research - Manage research projects - Present scientific information both formally and informally - Prepare papers for publication - Contribute to grant writing - Perform lab responsibilities as assigned - Work collaboratively and collegially as part of the team while developing skills needed as an independent scientist.   Knowledge, Skills, and Abilities Knowledge of the principles and practices of scientific theory and research; demonstrates skill in formulating and testing hypotheses; demonstrates ability to conduct scientific research analysis and summarize data and results; writes technical, scientific papers; writes grants and communicates effectively both orally and in writing; mentor students; provides analytic support and input to other projects in the group and guides/directs the work of less senior scientists.

The Bodine Lab is seeking a Post-doctoral Fellow. Incumbents at this level will be mentonerd and will plan, design and conduct research experiments; manage research projects; prepare reports and papers for publication, presentation and future research; contribute to grant writing and are encouraged to write applications for fellowships. Learn the complexities of research lab management and participate in various lab management responsibilities.

Responsible for professional social work services and assisting multiple sclerosis patients to include identifying medical assistance programs and mobility assistance programs; assisting patients with insurance and prior authorization questions, performing neuropsychological evaluations, counseling patients and/or patient care partners. Serves as an educational resource for patients/families for disease-oriented support. Provides case management services and may give presentations to a variety of audiences.   Essential Functions Assessment - Completes comprehensive psychosocial and other appropriate assessments for patients; may interview patients as well as their family members/significant others to gather relevant information; effectively uses professional skills, objectivity and insight to interpret data and to identify viable options.   Education & Resources - Gives presentations regarding the autoimmune disease clinic to patient groups, other health care providers, and potentially donors. Assists patients with health related issues acting as their educational resource for disease-oriented support; interprets and explains medical assistance, mobility assistance benefit programs to patients and helps with insurance and prior authorization questions.   Counseling & Support Services - Provides case management and counseling services as appropriate; provides advice, guidance, and emotional support and other assistance as needed to patients.   Treatment Input & Reporting - Presents regular informal oral presentations of progress and results to the supervisor and colleagues. Maintains the highest standards of ethical behavior.   Performs other duties as assigned by supervisor.

The Ahamed lab is looking for a full-time or part-time Research Technician. Our laboratory studies mouse models of heart diseases with a particular focus on fibrosis. We utilize state-of-the-art techniques in genetics, molecular biology, cell biology, and biochemistry. The position involves breeding of our mouse colony, performing experiments utilizing a variety of techniques, analyzing data, contributing to management and contributing to laboratory management and oversight.   Assists, as needed, with administering injections, medications, venipunctures, applying wound dressings, and with diagnostic procedures as directed by supervisor and/or consulting veterinarian.   Identify, prepare and perform a variety of research experiments according to protocol. Projects and assignments are typically non-routine and variable in nature. Receive no instruction on routine work, but receive instructions on new work or special assignments. Collect and present data to Manager or Principal Investigator.

Assist with our development of text-mining software to identify and evaluate statistical discrepancies and other errors within scientific papers. Specific duties will include code development in Python and deploying/testing it on a local web server that uses Flask. Flexible work schedule.

The Miller lab is currently hiring for a Research Technician who will design, perform and analyze complex research experiments. Organizes, interprets, and communicates data to supervisor and co-workers. Modifies protocols to improve processes. Documents work appropriately. Troubleshoots problems in lab. May provide guidance to research staff, graduate students, and post docs. Collaborates, builds constructive relationships, and effectively communicates with other members of the lab. Works independently, but seeks assistance when needed. Operates highly specialized equipment requiring moderate to high degree of skill. Expected to perform more advanced techniques after appropriate training. Ability to work well with others is essential.

We are looking for a highly motivated postdoctoral research fellow to join the multidisciplinary Stout Laboratory within the Aging & Metabolism (A&M) Research Program at OMRF. The fellow will investigate how sex hormones and their receptors modulate hypothalamic neurocircuitry and the sex-specific regulation of systemic metabolism during the aging process. The successful candidate will employ a wide range of techniques including stereotaxic injection of AAVs into the brain, chemogenetic approaches (DREADD), brain imaging, single-cell transcriptomics, in vivo metabolic assessments, and a variety of cellular & molecular biology techniques. The candidate will present their data regularly in laboratory meetings, local seminars and symposiums, and will have opportunities to present their work at national conferences. A requirement of the position is that the candidate must demonstrate ethical behavior at all times, a high level of scientific rigor, and must be detail oriented and able to work independently and as part of a team.   The Stout Laboratory and A&M Research Program welcome applicants from diverse backgrounds that thrive in a highly collaborative and supportive environment. We are strongly committed to providing individualized mentoring and assistance with career advancement through the implementation of a postdoctoral mentoring committee. The A&M Research Program, which currently consists of 13 highly collaborative investigators, provides an exceptional training environment in aging biology (Geroscience). The A&M Research Program also has a strong collaborative history with  faculty from the Oklahoma Center for Geroscience and Health Brain Aging at OUHSC which has resulted in a Geroscience Training Grant (T32 AG052363) that supports graduate students and postdoctoral fellows at OMRF and OUHSC. The collaborative program also houses the Oklahoma Nathan Shock Center of Excellence in Basic Biology of Aging (P30 AG050911), which provides pilot funding for junior investigators. OMRF also offers an annual grant writing course (F-troop) for graduate students and postdoctoral fellows that plan to prepare grant applications (F- or K-awards) for the NIH. The OMRF Postdoctoral Association offers additional training opportunities related to grant writing, presentation skills, and career development. The vibrant and highly collaborative environment within OMRF has resulted in the foundation being named the top large employer in the state of Oklahoma three times in the last five years.

Join a welcoming, passionate, dynamic, diverse, diligent organization and Human Resources team and make a difference! Enjoy ongoing career training and development, and a positive, supportive environment.   We seek an ace recruiter to lead the recruiting team and provide a variety of recruitment services. Strategically partner with hiring managers, build applicant pipelines, source candidates, write, post and advertise positions, attend career fairs, screen applicants, conduct interviews, check references, and administer other recruiting assistance while ensuring optimal customer service with a mission-oriented and DEIA mindset, compliance with Equal Employment Opportunity policies and Department of Labor regulations and laws. Develop and assist with the execution of social media, other marketing and proactive recruiting strategies by collaborating with HR, Public Affairs, and others. Assist with the implementation of diversity, equity, inclusion, and accessibility efforts. Generate and analyze AAP data in partnership with our external vendor and help initiate any necessary changes. May assist with oversight and coordination of summer programs.   Our future teammate will also help respond to routine and moderately complex HR inquiries with discretion and judgment and may contribute to other HR functions such as onboarding, immigration, employee record keeping and employee relations by collaborating with supervisors and HR team members to provide guidance, solutions, and options. Assist with certain compensation functions to include updating/developing job descriptions and career ladders and helping determine salaries for new hires. Provide project assistance, help coordinate employee functions with other HR team members, and perform other duties as assigned.

The Guthridge & James labs are seeking a highly motivated and organized individual to contribute to projects designed to deconstruct the drivers of autoimmune disease at the molecular level in both preclinical and advanced disease states. Studies characterizing the immune cells and their responses against pathogens and autoreactive responses at the cellular and tissue levels using advanced single-cell multiomic phenotyping approaches, high-dimnensional biomarker profiling, and spatial multiomic techniques. Duties will include both basic and advanced cell and molecular biology techniques, such as Luminex and Olink biomarker assays in addition to ELISAs, Western blotting. Single cell techniques including multi-parameter flow cytometry, high-dimensional mass cytometry (CyTOF), imaging mass cytometry (Hyperion), and single cell transcriptomics, proteomics and repertoire using the latest 10X genomics platforms.

The Lee laboratory at the Cardiovascular Biology Research Program (CVB) of OMRF is seeking Postdoctoral Fellows to lead research projects. Our NIH-funded research program (https://leelab.omrf.org/) investigates mechanisms linking mitochondrial and NAD+ metabolism to pathogenesis of cardiometabolic diseases. Fellows will have access to resources and equipment for cardiac physiology and electrophysiology, metabolism, cardiomyocyte and mitochondrial function, proteomics, metabolomics, informatics and spatial transcriptomics from the Lee lab, CVB, CMRO-CoBRE (https://cellularmetabolism-cobre.omrf.org/), OMRF core facilities (https://omrf.org/research-faculty/core-facilities/) and collaborations.   Candidates must be self-motivated, proactive and enthusiastic about their research career development. The Principal Investigator (PI) and the postdoctoral mentoring committee will be committed to prepare fellows for an independent research career. Candidates are expected to work independently and contribute intellectually to facilitate a stimulating environment within the research group and among research programs at OMRF. OMRF’s postdoctoral fellow association (https://omrf.org/about-omrf/education-outreach/postdoctoral-programs/postdoc-association/) seeks to enhance the training experience by providing scientific, social interaction opportunities and funds to support attendance at scientific meetings or workshops.   Successful candidates will have a recent doctoral degree (within 0-3 years or expect to receive the degree within a year) in cardiovascular physiology, biochemistry or related biomedical disciplines. First-authored publication(s) from the graduate work is expected. Prior research experience and publication(s) investigating cardiometabolic diseases in mouse model are required. Experience in echocardiography, electrophysiology and surgical techniques for heart disease is a plus.    

Completes required work order forms and follows up on repair orders to ensure maintenance is completed in a timely manner. Performs a variety of duties in the maintenance and repair of buildings and grounds including carpentry, electrical, plumbing, and repair tasks; performs minor troubleshooting, repairs, and adjustments on equipment, appliances, and/or machinery. Exercises discretion in identifying projects requiring the services of a higher skilled crafts person. Assists highly skilled workers involved in the adjustment, maintenance, part replacement and repair of equipment or machinery. Activates and deactivates building alarms and responds to alarm calls during and after regular work hours. Responds to the Foundation emergency telephone/radio and contacts the appropriate authority, i.e., fire department, Foundation security, police department, or contractors. Notifies management of any problems and status of the situation. Maintains a safe work environment by following safety rules and federal regulations. Perform other duties as assigned by supervisor.

Provide assistance and organization to multiple Principle Investigators (PIs) in the Arthritis and Clinical Immunology Research Program. Update and organize CVs and Biosketches for PIs. Assist in organizing bibliographies and published paper collections, monitoring for Public Access compliance. Assist in drafting and/or editing letters, regulatory documents such as IRB or IACUC applications. Organize and maintain records of grant effort distribution and monthly accounting reports. Monitor and notify PIs of various deadlines well in advance of due date for grant reporting and renewal, membership renewal, abstract, and meeting deadlines. Manage PI calendars. Gather timesheets and get PI signatures. Manage travel arrangements and reimbursements. Assist with purchasing office equipment and supplies. Assist with planning and arranging all aspects of visits for guest speakers, meetings, seminars, and symposia as required for department and PIs. Meet with PIs as needed to review and coordinate workloads, deadlines, etc., and provide feedback regarding completion of major tasks, office operations and any issues. Requesting or pulling publications. Must have a helpful orientation and positive attitude. Filing, copying, picking up/delivering mail, and other administrative tasks. Opportunities to learn grant and manuscript preparation and submission skills. Assists in the preparation of budgets; responsible for maintaining budgetary records and expenditures and other support items for federal grant applications. Edits scientific documents for grammar flow and clarity; ensures compliance with federal grant submission requirements.

The Guthridge Lab is seeking a Research Technician for the Biorepository which supports our clinical and translational research investigators. Candidates should be highly organized, motivated and team oriented. Duties will include all repository activities related to receipt, processing, storage, maintenance and records management of human blood and tissue samples related to studies and clinical trials in a CAP (College of American Pathologists) certified facility. Individual will need to be comfortable working in cold temperatures with appropriate personal safety protections and working with human samples.