Dr. A. Darise Farris is hiring a Clinical Research Nurse to coordinate and execute Sjögren’s research projects. We are seeking a highly motivated individual to work closely with principal investigators to assist with identification and recruitment of patients and controls into our clinical research projects. The coordinator will work in a Sjögren’s Research Clinic and will be engage directly with subjects participating in research projects performing nursing duties, sample collections, review and abstraction of data from medical records, interface with investigators and clinical coordinators at other research sites, manage and maintain regulatory documents including submissions/reports to the IRB. Comply with FDA, ICH/GCP, and HIPAA rules and regulations. Tasks require a high level of organizational skills and the ability to ask the right questions to determine proper course of action while following established standards and research protocols.   DUTIES:   1. Sjögren’s Research Clinic. Conducts research and assists researchers by recruiting patients, determining eligibility, and seeing patients through research studies including obtaining informed consent, administering questionnaires, taking medical histories, performing study procedures, assisting the clinicians performing invasive procedures, counseling patients, and performing all study related tasks as outlined in study protocols and in adherence with GCP, ICH, and HIPAA regulations.   2. Chart Review. Performs medical chart review to abstract data for research including but not limited to constructing medical history and medications chronology, evaluating disease progression, and mapping symptom and biomarker associations.   3. Communication. Liaises between principal investigator, patients, third party patient care service providers, members of the non-OMRF collaborating sites, and governing agencies to ensure strict adherence to protocol and regulations throughout study conduct. Excellent written and oral communications required.   4. Patient Care. Assesses and records symptoms, vital signs, and other patient information required for research protocols and to prepare patient for examination. Review records for documentation of study inclusion/exclusion criteria. Carries out physician orders for testing and treatment and coordinates follow-up care of patients. Assists patients with immediate post-procedure care after oral and ocular evaluations. 5. Sample Collection. Collects samples from patients including blood, urine, saliva, etc. Prepares samples for analysis or shipment. Collects all laboratory reports, data, and records. Excellent phlebotomy skills required.   6. Data Management. Gathers, organizes, analyzes, and submits patient and research data to principal investigators, scientists, and sponsors. Computer skills required.   7. As Needed. Performs various duties as needed to successfully fulfill the function of the position.

The Oklahoma Medical Research Foundation (OMRF) Arthritis and Clinical Immunology Department and Rheumatology Center of Excellence is recruiting two physician-investigator faculty members with clinical care and research interests in systemic autoimmune rheumatic diseases. These investigators will be expected to have or to develop vibrant clinical research programs, in areas such as clinical trials, cohort studies, health equity, outcomes research, or other patient-oriented investigation and would join our strong multi-disciplinary Rheumatology clinical care and research teams. Building on strong clinical research infrastructure with longitudinal cohorts, a cadre of talented clinical coordinators/clinical research nurses, diverse aspects of clinical research informatics and a CAP-certified biorepository, we invite qualified candidates to apply for a clinical investigative position focusing on lupus, Sjogren’s, rheumatoid arthritis, or UCTD. We are currently recruiting at the Assistant/Associate/Full Professor level and talented candidates at all levels are encouraged to apply. Successful applicants will: • Provide comprehensive, optimal, science-driven Rheumatology patient care • Receive generous, multi-year start-up package with significant, sustained salary and research support • Collaborate with basic scientists interested in Rheumatology patient-oriented translational research • Interact closely with Oklahoma University Health Sciences Center faculty and participate in OUHSC house staff and medical training programs • Contribute toward and enjoy access to:      o vibrant patient cohorts with associated patient care and clinical trials infrastructure      o extensive autoimmune disease and control biospecimen collections      o outstanding OMRF and ACI Clinical and Research Core facilities Rheumatology investigators also have access to a number of outstanding OMRF core facilities and state-of-the-art clinical facilities. Pilot programs are also available through the Oklahoma Shared Clinical & Translational Resources funding streams, as well as through the Oklahoma Center for Advancement of Science and Technology. Our clinicians provide outpatient care with no in-patient admission or consulting requirements. OMRF (http://omrf.org) is an independent, not-for-profit biomedical research institute adjacent to the University of Oklahoma Health Sciences Center (OUHSC) campus in Oklahoma City. OMRF investigators enjoy close scientific interactions with OUHSC faculty and participate in OUHSC graduate programs. For more information about the OMRF Rheumatology Center of Excellence, please visit: https://omrf.org/patient-studies/rheumatoid-arthritis/. For more information about the Arthritis and Clinical Immunology Research program, please visit: https://omrf.org/programs/arthritis-clinical-immunology-research-program/, https://omrf.org/research-faculty/research-centers/, and https://omrf.org/patient-studies/.

The Zhao Lab is looking for a part-time Laboratory Technician. The individual is expected to perform routine laboratory procedures according to standardized protocols and report results. The individual receives detailed instructions on assignments and regular supervision. This position provides an excellent opportunity to learn mouse genetics and molecular techniques. It also allows the individual to gain experience in cellular immunology research using flow cytometry.   Responsibilities will include:   - Genotyping by PCR, DNA electrophoresis and updating strain database.   - Making common buffer/solutions.   - Assisting other researchers in experiments by harvesting tissues from mice, staining cells with antibodies, and running samples on flow cytometer.

The Krishnan Lab is seeking a highly motivated individual for a full-time Research Technician to join the team. This lab is a part of the Gene and Human Disease Program at the Oklahoma Medical Research Foundation.   The Krishnan Lab studies metabolism of the evolutionary mutant model organism – blind cavefish – to better understand human metabolic diseases such as diabetes and obesity. We use modern genomic methods like ATAC-seq, Hi-C, RNA-seq, metabolomics etc. to decipher the gene regulatory networks in these fishes. The position involves basic molecular biology experiments and NGS data analysis using R programming. An ideal candidate will have experience in one of both fields and be willing to learn other aspects of the job. OMRF has a close relationship with OUHSC and if needed, the candidate will be supported for a Ph.D. candidate position at the University.

The Krishnan Lab is seeking a highly motivated and independent individual for a full-time postdoc in the Genes & Human Disease Research Program at the Oklahoma Medical Research Foundation.   The Krishnan Lab studies the metabolism of the evolutionary mutant model organism – blind cavefish – to better understand human metabolic diseases such as diabetes and obesity. We use modern genomic methods like ATAC-seq, Hi-C, RNA-seq, metabolomics etc. to decipher the gene regulatory networks in these fishes.

1. Performs basic animal care functions including daily health observations and cage changing. 2. Performs routine medical treatments under the direction of the supervisor and veterinarian. 3. Maintains a clean and safe working environment 4. Clean and sanitize assigned areas of facility per department SOP's. 5. Maintain quality control records. 6. Performs, as directed, safety compliance and uses Personal Protective Equipment (PPE), as needed. 7. Assist with monitoring facility environment, notify supervisor of any problems detected. 8. Carry out all duties in compliance with standards of oversight bodies (AAALAC, PHS, etc.) and department SOP's. 9. Maintains positive working relationships as a team player through problem solving issues, speaking positively about others, listening attentively and observing the Confidentiality of research needs. 10. Performs all other duties as assigned.

Perform perimeter security checks inside and outside of Foundation buildings. Monitor security cameras for unauthorized visitors and contacts appropriate authorities as needed. Responsible for noticing and appropriately reporting leaks, noises, and/or other signs that might indicate mechanical malfunction of equipment. Responsible for monitoring and inspecting mechanical equipment and securing laboratories, offices, and other assigned areas of Foundation during non-standard operating hours. Monitors gauges, dials, or other indicators to ensure machinery is working properly. Check labs for alarms and notify responsible parties. Secure laboratories, offices, and other assigned areas. Responds to Foundation emergency telephone/radio and contacts the appropriate authority, i.e., fire department, Foundation security, police department, contractors, or others. Notifies management of any problems and provides regular status checks of the situation. Monitors building automation system and alarms then alerts the appropriate parties if there is a problem. Assists in maintaining, cleaning, and organizing mechanical and storage areas. Assists in collecting and replacing Biohazardous waste boxes. Assists skilled workers with maintenance, part replacement, and repair of equipment and machinery. Responds to Foundation emergency telephone/radio and contacts appropriate authorities. Maintains a safe work environment by following safety rules and federal regulations.   Must be willing and able to work effectively independently due to nature of work hours. Performs physical activities to include bending, stretching, twisting, reaching, installing, lifting, balancing, mobilizing inside and outside of all Foundation property, stooping, and moving materials. Perform other duties as assigned.